Search on: LUTEINIZING HORMONE 
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Descriptor English:   Luteinizing Hormone 
Descriptor Spanish:   Hormona Luteinizante 
Descriptor Portuguese:   Hormônio Luteinizante 
Synonyms English:   ICSH (Interstitial Cell Stimulating Hormone)
Interstitial Cell-Stimulating Hormone
LH (Luteinizing Hormone)
Lutropin  
Tree Number:   D06.472.699.322.576.463
D06.472.699.631.525.343.463
D12.644.548.691.525.343.463
Definition English:   A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity. 
Indexing Annotation English:   do not confuse X ref LUTROPIN with PLACENTAL LUTEOTROPIN; for alpha subunit, coordinate with GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; LUTEINIZING HORMONE, BETA SUBUNIT is also available
See Related English:   Receptors, LH
 
History Note English:   2003 (1968); use ICSH 1963-1967 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   22739 
Unique Identifier:   D007986 

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